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Product Information:

JR14a

JR14a is a potent thiophene antagonist of human complement C3a receptor. JR14a shows selectivity for the human C3a receptor over C5a receptor. JR14a can suppress C3aR-mediated inflammation.

Cat. No.: EX-A5201    Purity: >98%
Chemical
Chemical structure of JR14a


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg585In-stock
50mg785In-stock
100mg1285In-stock
200mg2000In-stock
500mg3350In-stock


CAS No.2411440-41-8
Purity>98%
FormulaC25H26Cl2N4O3S
Mol Weight533.47
ColorWhite to light yellow
Statesolid powder
SolubilitySoluble in DMSO 50 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Rowley JA, et, al. Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity. J Med Chem. 2020 Jan 23;63(2):529-541.

CoACoA of JR14a

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