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Product Information:

JPD447

JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.

Cat. No.: EX-A10773    Purity: >98%
Chemical
Chemical structure of JPD447


For research only, Do not use for Human!

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CAS No.2883235-86-5
Purity>98%
FormulaC20H23FN4
Mol Weight338.4218
Colorwhite to off-white
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Workman SD, et al. Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. J Med Chem. 2021 Sep 23;64(18):13540-13550.

CoACoA of JPD447
Smiles:FC(C=C1)=CC=C1C2=C3N(N=C2)C(N4CCCCCC4)=CC(CC)=N3

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