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Product Information:

JP-2-196 alkyne

JP-2-196 alkyne is a covalent RNF126 chemical handle that binds to several other RING E3 ubiquitin ligases including RNF14, RNF40, RNF219, MID2, and LRSAM1. By facilitating E3 ligase recruitment, JP-2-196 alkyne induces proteasomal degradation of diverse target proteins. It serves as a modular scaffold for the design and synthesis of molecular glue degraders. JP-2-196 alkyne is an alkyne functionalized version of JP-2-196.

Cat. No.: EX-A12103    Purity: >98%
Chemical
Chemical structure of JP-2-196 alkyne


For research only, Do not use for Human!

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CAS No.2901113-25-3
Purity>98%
FormulaC18H20N2O3
Mol Weight312.363
Statesolid
Shelf Life>3 years if stored properly
StoragePure form 4℃, sealed storage, away from moisture and light, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
CoACoA of JP-2-196 alkyne
Smiles:O=C(C=CC(=O)N1CCN(CC#C)CC1)C2=CC=C(OC)C=C2

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