JNK3 inhibitor compound A53

JNK3 inhibitor compound A53 is a potent and selective JNK3 inhibitor (IC50 = 78 nM) that had significant inhibition (>80% at 1 μM) to only JNK3 in a 398-kinase panel.


Cat. No.: EX-A16615	Purity: >98%

	Chemical structure of JNK3 inhibitor compound A53

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	1685	Inquire
50mg	1985	Inquire
100mg	2485	Inquire

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Synonyms	JNK3 inhibitor cmp A53
CAS No.	3041063-63-9
Purity	>98%
Formula	C24H21Cl2N5O3S
Mol Weight	530.426

Reference:	[1]. Li, Zhongtang et al. “The structure-based optimization of 3-substituted indolin-2-one derivatives as potent and isoform-selective c-Jun N-terminal kinase 3 (JNK3) inhibitors and biological evaluation.” European journal of medicinal chemistry vol. 250 (2023): 115167. doi:10.1016/j.ejmech.2023.115167
CoA	CoA of JNK3 inhibitor compound A53

Smiles:	O=C1\C(\C=2C(N1)=CC=C(NC(=O)C3CCN(C)CC3)C2)=C\4/S\C(=N\C5=C(Cl)C(Cl)=CC=C5)\NC4=O


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