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Product Information:

JNJ-67569762

JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket (IC50 = 2.7 nM).

Cat. No.: EX-A13792    Purity: >98%
Chemical
Chemical structure of JNJ-67569762


For research only, Do not use for Human!

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CAS No.2380313-26-6
Purity>98%
FormulaC22H22F4N4O5S
Mol Weight530.492
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Rombouts FJR, et al. JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. J Med Chem. 2021 Oct 14;64(19):14175-14191.

CoACoA of JNJ-67569762
Smiles:FC[C@]1(C2=CC(NC(C3=NC=C(OC(F)(O4)F)C4=C3)=O)=CC=C2F)N=C([C@@](C)(CC1)S(CC)(=O)=O)N

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