JNJ-61432059

JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8.


Cat. No.: EX-A7780	Purity: >98%

	Chemical structure of JNJ-61432059

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	885	In-stock
100mg	1285	In-stock
200mg	2085	In-stock

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CAS No.	2035814-50-5
Purity	>98%
Formula	C25H22FN5O2
Mol Weight	443.4729
Color	white to off-white
State	solid powder
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Savall BM, et al. Discovery of Imidazo[1,2-a]pyrazines and Pyrazolo[1,5-c]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators. ACS Med Chem Lett. 2018 Dec 26;10(3):267-272.
CoA	CoA of JNJ-61432059

Smiles:	C1CN(CCC1O)C2=NC=CC3=C(C(=NN32)C4=CC=C(C=C4)F)C5=CC6=C(C=C5)NC(=O)C6


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