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Product Information:

JNJ-40411813

JNJ-40411813 (ADX-71149) is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.

Cat. No.: EX-A2902    Purity: >98%
Chemical
Chemical structure of JNJ-40411813


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg485In-stock
200mg700In-stock
500mg950In-stock
1g1450In-stock
5g4685In-stock


SynonymsADX-71149
CAS No.1127498-03-6
Purity>98%
FormulaC20H25ClN2O
Mol Weight344.878
Colorwhite to off-white
Statepowder
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Cid JM, et al. Discovery of 1-Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone (JNJ-40411813): A Novel Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor. J Med Chem. 2014 Aug 14;57(15):6495-512.
CoACoA of JNJ-40411813
Smiles:CCCCN1C=CC(N2CCC(CC2)C2=CC=CC=C2)=C(Cl)C1=O

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