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Product Information:

JNJ-38877605-d1

JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3 .

Cat. No.: EX-A8969    Purity: >98%
Chemical
Chemical structure of JNJ-38877605-d1


For research only, Do not use for Human!

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CAS No.1936472-36-4
Purity>98%
FormulaC19H13F2N7
Mol Weight378.3564
ColorWhite to off-white
StateSolid
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sikkema BJ, et al. Quantification and clinical validation of the selective MET kinase inhibitor DO-2 and its metabolites DO-5 and M3 in human plasma. J Pharm Biomed Anal. 2024 Jan 4;240:115962.

CoACoA of JNJ-38877605-d1
Smiles:FC(C1=CC=C(N=C([2H])C=C2)C2=C1)(F)C3=NN=C4N3N=C(C5=CN(C)N=C5)C=C4

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