JI051

JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity.


Cat. No.: EX-A3106	Purity: >98%

	Chemical structure of JI051

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	785	In-stock
1g	get quote
5g	get quote

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CAS No.	2234281-75-3
Purity	>98%
Formula	C22H24N2O3
Mol Weight	364.4376
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Perron A, et al. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. J Biol Chem.
CoA	CoA of JI051

Smiles:	O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC


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