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Product Information:

JAK2-IN-10

JAK2-IN-10 is a selective JAK2 V617F inhibitor with an IC50 value of ≤10 nM. JAK2-IN-10 can be used for the research of myeloproliferative neoplasms and other related diseases.

Cat. No.: EX-A13966    Purity: >98%
Chemical
Chemical structure of JAK2-IN-10


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg1120In-stock
10mg1680In-stock
25mg2480In-stock
50mg3380In-stock
100mg4600In-stock


CAS No.3035735-18-0
Purity>98%
FormulaC33H36FN9O2
Mol Weight612.7149
ColorWhite to off-white
StateSolid
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Seoyoung Cho, et al. Tricyclic urea compounds as jak2 v617f inhibitors. WO2024086273A1. 2024.05.25.

CoACoA of JAK2-IN-10
Smiles:O=C1N(C2=C3C(=C(N=C3NC=C2N1C)C4=CN(CC)N=C4F)C=5C=C6C(=CC5)N(C([2H])([2H])[2H])N=C6)[C@H]7CC[C@](NC(=O)C8CC8)(C)CC7

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