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Product Information:

Isoleucyl tRNA synthetase-IN-2

Isoleucyl tRNA synthetase-IN-2 (compound 36a) is a potent and selective isoleucyl-tRNA synthetase (IleRS) inhibitor, with a Ki,app of 114 nM .

Cat. No.: EX-A15144    Purity: >98%
Chemical
Chemical structure of Isoleucyl tRNA synthetase-IN-2


For research only, Do not use for Human!

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CAS No.2494195-61-6
Purity>98%
FormulaC22H33N5O8S
Mol Weight527.591
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. De Ruysscher D, et al. Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase. Bioorg Med Chem. 2020 Aug 1;28(15):115580.

CoACoA of Isoleucyl tRNA synthetase-IN-2
Smiles:O[C@H]([C@@H]([C@H](OC1)COS(NC([C@@H](N)[C@@H](C)CC)=O)(=O)=O)O)[C@@H]1OCCN2C=C(C3=CC=CC=C3)N=N2

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