Isochenodeoxycholic acid

Isochenodeoxycholic acid (isoCDCA) is a FXR agonist. Isochenodeoxycholic acid activates the activity of FXR and induces the mRNA expression of FXR target genes (Ostβ and Kng1). Isochenodeoxycholic acid serves as a substrate for the liver class I ADH γγ isozyme-mediated 3β-dehydrogenation reaction .


Cat. No.: EX-A10342	Purity: >98%

	Chemical structure of Isochenodeoxycholic acid

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	998	In-stock
100mg	1598	In-stock
250mg	2498	In-stock

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


Synonyms	isoCDCA
Synonyms 2	Urosodeoxycholic Acid EP Impurity K
CAS No.	566-24-5
Purity	>98%
Formula	C24H40O4
Mol Weight	392.572
Color	White to off-white
State	Solid
Solubility	soluble in DMSO/Ethanol
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, protect from light; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zaufel A, et al. Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions. Biochim Biophys Acta Mol Basis Dis. 2021;1867(8):166153. [2]. Marschall HU, et al. Human liver class I alcohol dehydrogenase gammagamma isozyme: the sole cytosolic 3beta-hydroxysteroid dehydrogenase of iso bile acids. Hepatology. 2000 Apr;31(4):990-6.
CoA	CoA of Isochenodeoxycholic acid

Smiles:	C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@H](CC4)O)([H])C[C@H]3O)C


		Search