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Product Information:

IRE1α kinase-IN-5

IRE1α kinase-IN-5 (compound 7) is a potent IRE1α inhibitor with an Ki of 98 nM. IRE1α kinase-IN-5 is the ATP-competitive ligands of IRE1α .

Cat. No.: EX-A9105    Purity: >98%
Chemical
Chemical structure of IRE1α kinase-IN-5


For research only, Do not use for Human!

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SynonymsIRE1alpha kinase-IN-5
CAS No.2771006-47-2
Purity>98%
FormulaC28H30N6O3S
Mol Weight530.641
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Feldman HC, et al. ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 Nov;17(11):1148-1156.

CoACoA of IRE1α kinase-IN-5
Smiles:O=S(NC(C1=C2C=CC=C1)=CC=C2OC3=NC=CC=C3C4=NC(N[C@H]5CC[C@H](N)CC5)=NC=C4)(C6CC6)=O

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