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Product Information:

IPSU

IPSU is a selective, orally available and brain penetrant OX2R antagonist with a pKi of 7.85.

Cat. No.: EX-A7238    Purity: >98%
Chemical
Chemical structure of IPSU


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg785In-stock
200mg1185In-stock
500mg1785In-stock
1g2585In-stock


CAS No.1373765-19-5
Purity>98%
FormulaC23H27N5O2
Mol Weight405.4928
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : ? 30 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 year
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Betschart C, et al. Identification of a novel series of orexin receptor antagonists with a distinct effect on sleeparchitecture for the treatment of insomnia. J Med Chem. 2013 Oct 10;56(19):7590-607.

[2]. Callander GE, et al. Kinetic properties of "dual" orexin receptor antagonists at OX1R and OX2R orexin receptors. Front Neurosci. 2013 Dec 3;7:230.

[3]. Hoyer D, et al. Distinct effects of IPSU and suvorexant on mouse sleep architecture.

CoACoA of IPSU

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