IPPQ

IPPQ is a small molecule that selectively target the interface between the N-type calcium (CaV2.2) channel and CaVβ, specifically binds to CaVβ2a and inhibits CaVβ2's interaction with CaV.2-AID (alpha interacting domain).


Cat. No.: EX-A16346	Purity: >98%

	Chemical structure of IPPQ

For research only, Do not use for Human!

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CAS No.	1070445-21-4
Purity	>98%
Formula	C25H27N5O2
Mol Weight	429.5142
State	solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Khanna, Rajesh et al. “Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.” Pain vol. 160,7 (2019): 1644-1661. doi:10.1097/j.pain.0000000000001524
CoA	CoA of IPPQ

Smiles:	O=C(NCC=1N=C2C=CC=CC2=C(N1)NCCCC=3C=CC=CC3)CC=4C(=NOC4C)C


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