IONIS-FB-LRx sodium

Sefaxersen sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). Sefaxersen sodium effectively reduces circulating levels of CFB, and can be used for geographic atrophy (GA) research.


Cat. No.: EX-A11334A	Purity: >98%

	Chemical structure of IONIS-FB-LRx sodium

For research only, Do not use for Human!

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Synonyms	RG6299 sodium
CAS No.	2272983-11-4
Purity	>98%
Mol Weight	0.0
Color	Off-white to light yellow
State	solid
Solubility	H2O : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Dreismann AK, et al. Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway. Immunol Rev. 2022 Nov 12. [2]. Mahmoudzadeh R, et al. Emerging treatments for geographic atrophy in age-related macular degeneration. Curr Opin Ophthalmol. 2021 May 1;32(3):294-300.
CoA	CoA of IONIS-FB-LRx sodium


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