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Product Information:

ARV-110

ARV-110 (Bavdegalutamide) is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR.

Cat. No.: EX-A5017    Purity: >98%
ARV-110
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg450In-stock
100mg550In-stock
250mg800In-stock
500mg1200In-stock
5g5950In-stock
10g9425In-stock


SynonymsBavdegalutamide
CAS No.2222112-77-6
Purity>98%
FormulaC41H43ClFN9O6
Mol Weight812.288
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Neklesa T, et al. ARV-110: An oral androgen receptor PROTAC degrader for prostate cancer. Journal of Clinical Oncology. Journal of Clinical Oncology March 1 2019 37(7_suppl):259.

[2]. Zeng S, et al. Proteolysis targeting chimera (PROTAC) in drug discovery paradigm: Recent progress and future challenges. Eur J Med Chem. 2021 Jan 15;210:112981. doi: 10.1016/j.ejmech.2020.112981. Epub 2020 Oct 31. PMID: 33160761.

[3]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. doi: 10.1016/j.apsb.2019.08.001. Epub 2019 Aug 13. PMID: 32082969; PMCID: PMC7016280.
Data SheetData sheet of ARV-110
CoACoA of ARV-110

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