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Product Information:

Indoluidin D

Indoluidin D is a potent selective dihydroorotate dehydrogenase (DHODH) inhibitor, promotes myeloid differentiation and inhibits the proliferation of acute promyelocytic leukemia HL-60 cells.

Cat. No.: EX-A8137    Purity: >98%
Chemical
Chemical structure of Indoluidin D


For research only, Do not use for Human!

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Purity>98%
FormulaC28H28N4O2
Mol Weight452.5475
Statesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kawatani M, Aono H, Shimizu T, Ohkura S, Hiranuma S, Muroi M, Ogawa N, Ohishi T, Ohba SI, Kawada M, Yamazaki K, Dan S, Osada H. Identification of Dihydroorotate Dehydrogenase Inhibitors─Indoluidins─That Inhibit Cancer Cell Growth. ACS Chem Biol. 2021 Nov 19;16(11):2570-2580. doi: 10.1021/acschembio.1c00625. Epub 2021 Nov 3. PMID: 34730931.

CoACoA of Indoluidin D
Smiles:O=C(N[C@@H](C(NC1=CC=C(C=C1)C)=O)CC2=CNC3=C2C=CC=C3)[C@@H]4NCC5=C(C4)C=CC=C5

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