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Product Information:

Indirubin-E804

Indirubin Derivative E804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R.

Cat. No.: EX-A9524    Purity: >98%
Chemical
Chemical structure of Indirubin-E804


For research only, Do not use for Human!

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CAS No.854171-35-0
Purity>98%
FormulaC20H19N3O4
Mol Weight365.3826
ColorBrown to reddish brown
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cheng X, et al. Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule. J Med Chem. 2017 Jun 22;60(12):4949-4962.

CoACoA of Indirubin-E804
Smiles:O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C/3=N/OCCC(O)CO

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