INCB053914

INCB053914 is an orally active, ATP-competitive pan-PIM kinase inhibitor. INCB053914 phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines.


Cat. No.: EX-A2737A	Purity: >98%

	Chemical structure of INCB053914

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	850	In-stock
50mg	1300	In-stock
100mg	1950	In-stock
200mg	2950	In-stock

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CAS No.	1620012-39-6
Purity	>98%
Formula	C26H26F3N5O3
Mol Weight	513.5115
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Koblish H, et al. Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies. PLoS One. 2018 Jun 21;13(6):e0199108.
CoA	CoA of INCB053914

Smiles:	C[C@H]1CN(C2=C3CC[C@@H](O)C3=NC=C2NC(C4=NC(C5=C(F)C=CC=C5F)=C(F)C=C4)=O)C[C@@H](N)[C@@H]1O


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