IMB-301

IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G), interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G. IMB-301 inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM). Human APOBEC3G is a restriction factor that inhibits human immunodeficiency 1 virus (HIV-1) replication.


Cat. No.: EX-A5166	Purity: >98%

	Chemical structure of IMB-301

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	385	In-stock
25mg	585	In-stock
50mg	885	In-stock
100mg	1285	In-stock
200mg	1985	In-stock

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CAS No.	64009-84-3
Purity	>98%
Formula	C19H17Cl2FN2O
Mol Weight	379.255
Color	Colorless to light yellow
State	Oil
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Pure form -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhou, Jinming, et al. Applications of the IMB-301 in antiviral drugs is prepared. CN108261413A.
CoA	CoA of IMB-301

Smiles:	FC1=CC=C(OCCC(C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)C=C1


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