IM-54

IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death.


Cat. No.: EX-A6831	Purity: >98%

	Chemical structure of IM-54

For research only, Do not use for Human!

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CAS No.	861891-50-1
Purity	>98%
Formula	C19H23N3O2
Mol Weight	325.4048
Color	Light yellow to orange
State	solid powder
Solubility	Soluble in DMSO 50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20°C, stored under nitrogen; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kosuke Dodo, et al. Indolylmaleimide Derivative IM-17 Shows Cardioprotective Effects in Ischemia-Reperfusion Injury. ACS Med Chem Lett. 2018 Mar 8; 9(3): 182-187. [2]. Mikiko Sodeoka, et al. Development of selective inhibitors of necrosis. Chem Rec. 2010 Oct;10(5):308-14.
CoA	CoA of IM-54


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