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Product Information:

Illudin S

Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells.

Cat. No.: EX-A5056    Purity: >98%
Chemical
Chemical structure of Illudin S


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg1245In-stock
100mg2272In-stock
250mgget quoteIn-stock
500mgget quoteIn-stock
1gget quoteIn-stock


CAS No.1149-99-1
Purity>98%
FormulaC15H20O4
Mol Weight264.3169
ColorWhite to yellow
Statesolid
SolubilitySoluble in DMSO 50 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hansruedi Glatt, et al. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Arch Toxicol . 2014 Jan;88(1):161-9.

[2]. Nicolaas G J Jaspers, et al. Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways. DNA Repair (Amst). 2002 Dec 5;1(12):1027-38.

[3]. Illudin S, the sole antiviral compound in mature fruiting bodies of Omphalotus illudens

[4]. M J Kelner, et al. Preclinical evaluation of illudins as anticancer agents. Cancer Res. 1987 Jun 15;47(12):3186-9.

CoACoA of Illudin S

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