IGS-1.76

IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently.


Cat. No.: EX-A7539	Purity: >98%

	Chemical structure of IGS-1.76

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	685	In-stock
50mg	985	In-stock
100mg	1685	In-stock
200mg	2485	In-stock
500mg	qet quote	In-stock
1g	qet quote	In-stock

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CAS No.	313480-47-6
Purity	>98%
Formula	C22H18N2OS
Mol Weight	358.456
Color	White to off-white
State	solid powder
Solubility	DMSO : 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Carlos Roca, et al. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J Med Chem. 2018 Jul 26;61(14
CoA	CoA of IGS-1.76


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