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Product Information:

IGF-1R modulator 1

IGF-1R modulator 1 (Example 5) is an IGF-1R modulator, with EC50s of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), 0.39 μM (TrkB). IGF-1R modulator 1 can be used for research of diseases characterised by impaired signalling of neurotrophins and/or other trophic factors, such as Alzheimer's disease .

Cat. No.: EX-A16203    Purity: >98%
Chemical
Chemical structure of IGF-1R modulator 1


For research only, Do not use for Human!

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CAS No.2375424-89-6
Purity>98%
FormulaC22H17N3O4
Mol Weight387.3881
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Gunnar Nordvall, et al. Triazine derivatives for treating diseases relating to neurotrophins. Patent. WO2019162702.

CoACoA of IGF-1R modulator 1
Smiles:O=C1NC(=O)N(C2=CC=C(OC=3C=CC=CC3)C(=C2)C)C(=O)N1C=4C=CC=CC4

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