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Product Information:

IFN alpha-IFNAR-IN-1

IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3- L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM) .

Cat. No.: EX-A8032    Purity: >98%
Chemical
Chemical structure of IFN alpha-IFNAR-IN-1


For research only, Do not use for Human!

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CAS No.844882-93-5
Purity>98%
FormulaC18H17NS
Mol Weight279.399
ColorLight yellow to yellow
StateSolid-Liquid Mixture
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePure form   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Geppert T, et al. Immunosuppressive small molecule discovered by structure-based virtual screening for inhibitors of protein-protein interactions. Angew Chem Int Ed Engl. 2012 Jan 2;51(1):258-61.

CoACoA of IFN alpha-IFNAR-IN-1
Smiles:CNCC1=CC=CC=C1SC2=CC=CC3=CC=CC=C32

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