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Product Information:

IDO1/2-IN-1 hydrochloride

IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active .

Cat. No.: EX-A10708    Purity: >98%
Chemical
Chemical structure of IDO1/2-IN-1 hydrochloride


For research only, Do not use for Human!

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CAS No.2310286-60-1
Purity>98%
FormulaC16H19BrClFN8O4
Mol Weight521.729
SolubilitySoluble in DMSO
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. He X, et al. Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy. J Med Chem. 2021;64(24):17950-17968.

CoACoA of IDO1/2-IN-1 hydrochloride
Smiles:FC1=CC=C(C=C1Br)/N=C(C2=NON=C2NCCN3N=NC(COCCO)=C3)/NO.[H]Cl

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