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Product Information:

Ibrexafungerp citrate

MK-3118 (SCY-078, Ibrexafungerp), a glucan synthase inhibitor, is used potentially for the treatment of candida infection and aspergillosis.

Cat. No.: EX-A7291A    Purity: >98%
Chemical
Chemical structure of Ibrexafungerp citrate


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg1400In-stock
50mg2200In-stock
100mg3200In-stock
250mg5600In-stock
500mgget quoteIn-stock
1gget quoteIn-stock


SynonymsMK-3118 citrate
Synonyms 2SCY-078 citrate
CAS No.1965291-08-0
Purity>98%
FormulaC50H75N5O11
Mol Weight922.1574
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lepak, Alexander J et al. “Pharmacodynamic target evaluation of a novel oral glucan synthase inhibitor, SCY-078 (MK-3118), using an in vivo murine invasive candidiasis model.” Antimicrobial agents and chemotherapy vol. 59,2 (2015): 1265-72.

[2]. Jiménez-Ortigosa, Cristina et al. “Enfumafungin derivative MK-3118 shows increased in vitro potency against clinical echinocandin-resistant Candida Species and Aspergillus species isolates.” Antimicrobial agents and chemotherapy vol. 58,2 (2014): 1248-51.

[3]. Pfaller, Michael A et al. “Activity of MK-3118, a new oral glucan synthase inhibitor, tested against Candida spp. by two international methods (CLSI and EUCAST).” The Journal of antimicrobial chemotherapy vol. 68,4 (2013): 858-63.

[4]. Pfaller, Michael A et al. “In vitro activity of a new oral glucan synthase inhibitor (MK-3118) tested against Aspergillus spp. by CLSI and EUCAST broth microdilution methods.” Antimicrobial agents and chemotherapy vol. 57,2 (2013): 1065-8.

CoACoA of Ibrexafungerp citrate

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