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Product Information:

Iberin

Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC50 of 2.3 μM in HL60 cell. Iberin induces apoptosis.

Cat. No.: EX-A6930    Purity: >98%
Chemical
Chemical structure of Iberin


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg750In-stock
100mg1050In-stock
200mg1550In-stock
500mgget quoteIn-stock
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SynonymsNSC 321801
CAS No.505-44-2
Purity>98%
FormulaC5H9NOS2
Mol Weight163.261
ColorColorless to light yellow
StateLiquid
SolubilitySoluble in DMSO, Ethanol
Shelf Life>2 years if stored properly
StoragePure form -Solution, -20°C, 2 years.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Jakubikova J, et al. Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Res. 2005 Sep-Oct;25(5):3375-86.

[2]. Jadhav U, et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells.

[3]. Jadhav U, et al. Dietary isothiocyanate iberin inhibits growth and induces apoptosis in human glioblastoma cells. J Pharmacol Sci. 2007 Feb;103(2):247-51.

[4]. Jakobsen TH, et al. Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorumsensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Apr;78(7):2410-21.

[5]. Munday R, et al. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71.

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