IAXO-102

IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development.


Cat. No.: EX-A3691	Purity: >98%

	Chemical structure of IAXO-102

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	1720	In-stock
500mg	get quote	In-stock
1g	get quote	In-stock

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CAS No.	1115270-63-7
Purity	>98%
Formula	C35H71NO5
Mol Weight	585.9419
Color	white to off-white
State	solid
Solubility	Soluble in Ethanol/DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Huggins C, et al. A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development. Atherosclerosis. 2015 Oct;242(2):563-70.
CoA	CoA of IAXO-102

Smiles:	CCCCCCCCCCCCCCO[C@@H]1[C@H]([C@@H]([C@@H](CN)O[C@@H]1OC)O)OCCCCCCCCCCCCCC


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