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Product Information:

IACS-9439

IACS-9439 is a potent, highly selective, and orally bioavailable CSF1R inhibitor. IACS-9439 led to a dose-dependent reduction in macrophages, promoted macrophage polarization toward the M1 phenotype, and led to tumor growth inhibition in MC38 and PANC02 syngeneic tumor models.

Cat. No.: EX-A7207    Purity: >98%
Chemical
Chemical structure of IACS-9439


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
200mg35004-6 weeks


SynonymsIACS9439
CAS No.2231259-36-0
Purity>98%
FormulaC23H27N7O3S
Mol Weight481.571
Statesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Czako, Barbara et al. “Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R.” Journal of medicinal chemistry vol. 63,17 (2020): 9888-9911.

CoACoA of IACS-9439

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