Inhibitor Specialist 
Product Information:
| Cat. No.: EX-A5485 | Purity: >98% |
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| Chemical structure of HT61 |
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| Synonyms | HY-50A |
|---|---|
| Synonyms 2 | HT-61 |
| CAS No. | 936622-80-9 |
| Purity | >98% |
| Formula | C26H24N2O |
| Mol Weight | 380.4816 |
| Color | yellow |
| State | solid powder |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Frapwell CJ, Skipp PJ, Howlin RP, Angus EM, Hu Y, Coates ARM, Allan RN, Webb JS. Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02073-19. doi: 10.1128/AAC.02073-19. PMID: 32122902; PMCID: PMC7179629.
[2]. Amison RT, Faure ME, O'Shaughnessy BG, Bruce KD, Hu Y, Coates A, Page CP. The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. Pulm Pharmacol Ther. 2020 Apr;61:101884. doi: 10.1016/j.pupt.2019.101884. Epub 2019 Dec 27. PMID: 31887372. [3]. Hubbard AT, Coates AR, Harvey RD. Comparing the action of HT61 and chlorhexidine on natural and model Staphylococcus aureus membranes. J Antibiot (Tokyo). 2017 Oct;70(10):1020-1025. doi: 10.1038/ja.2017.90. Epub 2017 Aug 2. PMID: 28765589. |
| CoA | CoA of HT61 |
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