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Product Information:

HSN608

HSN608 is an orally active, potent RET G810 mutant inhibitor. HSN608 inhibits G810C, G810R, G810D. HSN608 induces Apoptosis. HSN608 inhibits the Selpercatinib -resistant RET(G810C) CDX tumors .

Cat. No.: EX-A8044    Purity: >98%
Chemical
Chemical structure of HSN608


For research only, Do not use for Human!

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CAS No.2234239-90-6
Purity>98%
FormulaC29H26F3N7O
Mol Weight545.5582
 
 
Reference:  

[1].Khatri U, et al. Targeting RET Solvent-Front Mutants with Alkynyl Nicotinamide-Based Inhibitors. Mol Cancer Ther. 2023 Jun 1;22(6):717-725.

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