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Product Information:

HSK39004

PDE3/4-IN-3 (Compound 7) is an orally active dual PDE3/4 inhibitor with IC50 s of 0.17 and ≤50 nM for PDE3A and PDE4B2, respectively. PDE3/4-IN-3 significantly inhibits methacholine-induced bronchoconstriction in guinea pigs. PDE3/4-IN-3 can be used for chronic obstructive pulmonary disease (COPD) and asthma research .

Cat. No.: EX-A16444    Purity: >98%
Chemical
Chemical structure of HSK39004


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mgget quote


CAS No.2939748-69-1
Purity>98%
FormulaC26H31N5O4
Mol Weight480.5739
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yi L, et al. Tricyclic fused heterocyclic pde3/4 dual inhibitor and use thereof. WO2023109802A1. 2023-06-22.

CoACoA of HSK39004
Smiles:O=C1N2C(C=3C(=CC(OC)=C(OC([2H])([2H])[2H])C3)CC2)=C/C(=N\C4=C(C)C=C(C)C=C4C)/N1CCNC(N)=O

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