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Product Information:

HSGN-94

HSGN-94 is a potent antimicrobial agent with lipoteichoic acid (LTA) biosynthesis inhibition. HSGN-94 inhibits drug-resistant Gram-positive bacteria with MIC values of 0.25-2 μg/mL. HSGN-94 inhibits biofilm formation of MRSA and Vancomycin-resistant Enterococci. HSGN-94 also inhibits pro-inflammatory cytokines, exhibits in vivo efficacy in an MRSA murine wound infection model.

Cat. No.: EX-A10077    Purity: >98%
Chemical
Chemical structure of HSGN-94


For research only, Do not use for Human!

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CAS No.2570797-85-0
Purity>98%
FormulaC23H23F3N4O4S
Mol Weight508.513
Colorwhite to off-white
Statesolid
Solubilitysoluble in DMSO: >50 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃ 2 years; protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Naclerio GA, et al. Mechanistic Studies and In Vivo Efficacy of an Oxadiazole-Containing Antibiotic. J Med Chem. 2022 May 12;65(9):6612-6630.

CoACoA of HSGN-94
Smiles:N(C(=O)C1=CC=C(S(=O)(=O)N2C[C@H](C)C[C@H](C)C2)C=C1)C=3OC(=NN3)C4=CC=C(C(F)(F)F)C=C4

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