HSD17B13-IN-7

HSD17B13-IN-7 (compound 1), a fluorophenol-containing compound, is a potent HSD17B13 inhibitor with IC50s of 0.18 μM and 0.25 μM β-estradiol and Leukotriene B4 as substrates, respectively. HSD17B13-IN-7 is a potent N-methyl-D-aspartate (NMDA) NR2B receptor antagonist. HSD17B13-IN-7 has the potential for non-alcoholic fatty liver disease research.


Cat. No.: EX-A8951	Purity: >98%

	Chemical structure of HSD17B13-IN-7

For research only, Do not use for Human!

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CAS No.	863564-16-3
Purity	>98%
Formula	C21H24FNO4
Mol Weight	373.418
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Shenping Liu, et al. Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13. Nat Commun. 2023 Aug 24;14(1):5158.
CoA	CoA of HSD17B13-IN-7

Smiles:	FC1=C(O)C=CC(C(NC[C@]2(O)CC[C@H](COC3=CC=CC=C3)CC2)=O)=C1


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