HS-1371

HS-1371 is a potent RIP3 kinase inhibitor with an IC50 of 20.8 nM. It binds to the ATP binding pocket of RIP3 and inhibits ATP binding to prevent RIP3 enzymatic activity in vitro.


Cat. No.: EX-A2073	Purity: >98%

	Chemical structure of HS-1371

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	385	In-stock
100mg	500	In-stock
250mg	825	In-stock
500mg	1185	In-stock
1g	1785	In-stock
2g	3200	In-stock

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CAS No.	2158197-70-5
Purity	>98%
Formula	C24H24N4O
Mol Weight	384.4736
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Park, Han-Hee et al. HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis. Experimental & molecular medicine vol. 50,9 1-15. 20 Sep. 2018
CoA	CoA of HS-1371

Smiles:	CC1=CC=C(OC2=CC=NC3=CC(=CC=C23)C2=CN(N=C2)C2CCNCC2)C=C1


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