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Product Information:

HPK1-IN-7

HPK1-IN-7 is a potent, orally active HPK1 (hematopoietic progenitor kinase 1, MAP4K1) inhibitor . HPK1-IN-7 shows selectivity against IRAK4 (59 nM) and GLK (140 nM).

Cat. No.: EX-A5396    Purity: >98%
Chemical
Chemical structure of HPK1-IN-7


For research only, Do not use for Human!

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CAS No.2320462-65-3
Purity>98%
FormulaC24H22N6O4
Mol Weight458.4693
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 125 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Degnan AP, et al. Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1. ACS Med Chem Lett. 2021;12(3):443-450. Published 2021 Feb 19.
CoACoA of HPK1-IN-7

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