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Product Information:

homo-vk-ii-36

SOICR-IN-1 (compound 32) is a store-overload induced calcium release (SOICR) inhibitor with an IC50 value of 14.6 μM. SOICR-IN-1 can be used for the research of cardiac arrhythmias .

Cat. No.: EX-A8547    Purity: >98%
Chemical
Chemical structure of homo-vk-ii-36


For research only, Do not use for Human!

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SynonymsHomo-VK-II-36
CAS No.1479049-35-8
Purity>98%
FormulaC27H28N2O5
Mol Weight460.5216
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 66.67 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent  -20°C, 1 year
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Smith CD, et al. Novel carvedilol analogues that suppress store-overload-induced Ca2+ release. J Med Chem. 2013 Nov 14;56(21):8626-55.

CoACoA of homo-vk-ii-36
Smiles:O=C1N(CCOC2=CC=CC=C2OC)CC(CCOC3=CC=CC(N4)=C3C5=C4C=CC=C5)OC1

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