HOIPIN-8 sodium

HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. HOIPIN-8 is a HOIPIN-1 derivative. HOIPIN-1 is a promising tool to explore the cellular functions of LUBAC.


Cat. No.: EX-A7795A	Purity: >98%

	Chemical structure of HOIPIN-8 sodium

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	416	in_stock
25mg	816	in_stock
50mg	1155	in_stock
100mg	1692	in_stock
200mg	2377	in_stock
1g	5639	in_stock

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Synonyms	HOIPIN-8 sodium salt
CAS No.	2519537-70-1
Purity	>98%
Formula	C23H15F2N4NaO3
Mol Weight	456.3768
Color	Off-white to light yellow
State	solid powder
Solubility	DMSO : 50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Ken Katsuya, et al. Small-molecule Inhibitors of Linear Ubiquitin Chain Assembly Complex (LUBAC), HOIPINs, Suppress NF-κB Signaling. Biochem Biophys Res Commun. 2019 Feb 12;509(3):700-706.
CoA	CoA of HOIPIN-8 sodium

Smiles:	O=C(O[Na])C1=CC=C(C2=CN(C)N=C2)C=C1/C=C/C(C3=C(F)C=C(C4=CNN=C4)C=C3F)=O


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