HOIPIN-1

HOIPIN-1 (JTP-0819958) is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM. HOIPIN-1 suppress LUBAC-mediated NF-kB activation in vitro.


Cat. No.: EX-A5121	Purity: >98%

	Chemical structure of HOIPIN-1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	385	In-stock
250mg	550	In-stock
500mg	850	In-stock
1g	1365	In-stock

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Synonyms	JTP-0819958
CAS No.	2470242-33-0
Purity	>98%
Formula	C17H13NaO4
Mol Weight	304.2725
Color	White to light yellow
State	solid powder
Solubility	Soluble in DMSO 5 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture and light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Katsuya K, et al. Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling. Biochem Biophys Res Commun. 2019 Feb 12;509(3):700-706.
CoA	CoA of HOIPIN-1

Smiles:	O=C(O[Na])C1=CC=CC=C1/C=C/C(C2=CC=CC=C2OC)=O.[(E)]


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