hMC1R agonist 1

hMC1R agonist 1 is a selective hMC1R agonist. hMC1R agonist 1 activates adenylate cyclase to induce intracellular cAMP accumulation. hMC1R agonist 1 can be used for the research of immune-inflammatory disorders .


Cat. No.: EX-A9659	Purity: >98%

	Chemical structure of hMC1R agonist 1

For research only, Do not use for Human!

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CAS No.	3028881-87-7
Purity	>98%
Formula	C54H70N14O8S2
Mol Weight	1107.353
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture, 1 year; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tomassi S, et al. CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists. J Med Chem. 2022;65(5):4007-4017.
CoA	CoA of hMC1R agonist 1

Smiles:	C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H](NC([C@H](CCCC)NC(C)=O)=O)CSCC=6C=C(CSC[C@@H](C(N)=O)NC3=O)C=CC6


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