HIV-1 inhibitor-64

HIV-1 inhibitor-64 (Compound 7c) is a wild-type HIV-1 inhibitor that effectively suppresses the activity of HIV-1 mutants E138K/Q148K and G140S/Q148R with EC50 values of 62.5 nM and 11.3 nM, respectively. HIV-1 inhibitor-64 exhibits antiviral activity and can be used in the research of AIDS .


Cat. No.: EX-A17338	Purity: >98%

	Chemical structure of HIV-1 inhibitor-64

For research only, Do not use for Human!

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CAS No.	2919019-36-4
Purity	>98%
Formula	C19H19F2N3O4
Mol Weight	391.3687

Reference:	[1].Mahajan, et al. "N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants." ACS Infectious Diseases (2024).
CoA	CoA of HIV-1 inhibitor-64

Smiles:	O=C(N(C(C)C)CCN1C=C2C(NCC3=C(F)C=C(F)C=C3)=O)C1=C(O)C2=O


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