HG6-64-1

HG6-64-1 (HMSL 10017-101-1) is a B-raf kinase modulator.HG6-64-1 modulates B-raf kinase activity, including the V600E mutant form and the drug-resistant gatekeeper mutation T529I. HG6-64-1 is a germinal center kinase inhibitor. HG6-64-1 induces cell cycle arrest and apoptosis. HG6-64-1 can be used for the research of diffuse large B-cell lymphoma (DLBCL).


Cat. No.: EX-A11056	Purity: >98%

	Chemical structure of HG6-64-1

For research only, Do not use for Human!

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Synonyms	HMSL 10017-101-1
CAS No.	1315329-43-1
Purity	>98%
Formula	C32H34F3N5O2
Mol Weight	577.6399
Color	White to yellow
State	Solid
Solubility	DMSO : 75 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, protect from light, stored under nitrogen; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Nathanael S. Gray. Type ii raf kinase inhibitors. WO2011090738A2.
CoA	CoA of HG6-64-1

Smiles:	O=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(/C=C/C4=CN=C(NC=C5)C5=C4OC)=C3


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