background


Product Information:

HDAC8-IN-12

HDAC8-IN-12 (compound 5k) is a non-hydroxamic acid, selective inhibitor of HDAC8 (IC50: 0.12 nM) and a potent inhibitor of breast cancer. HDAC8-IN-12 triggers anti-tumor immunity by activating T cells, increasing the proportion of M1 macrophages and decreasing the proportion of M2 macrophages. HDAC8-IN-12 (50 mg/kg) exerts tumor suppressive effects in an orthotopic mouse model of breast cancer.

Cat. No.: EX-A12825    Purity: >98%
Chemical
Chemical structure of HDAC8-IN-12


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1gget quoteInquire


CAS No.3028095-13-5
Purity>98%
FormulaC16H17N3O5
Mol Weight331.3233
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Natural Derivatives of Selective HDAC8 Inhibitors with Potent in Vivo Antitumor Efficacy against Breast Cancer

CoACoA of HDAC8-IN-12
Smiles:CN(/C1=C\C2=CC=C(C(OC)=C2)/C=C/C(NO)=O)C(CNC1=O)=O

KEYWORDS: buy HDAC8-IN-12 | HDAC8-IN-12 supplier | purchase | cost | manufacturer | order | distributor | buy 3028095-13-5 | 3028095-13-5 supplier