HDAC-IN-100

HDAC-IN-100 is a histone deacetylase inhibitor with an IC50 of 0.038 μM against HDAC1, 0.283 μM against HDAC2, and 0.586 μM against HDAC3. HDAC-IN-100 acts as a chemosensitizer and apoptosis inducer, activates caspase 3/7, and reverses Cisplatin (HY-17394) resistance. HDAC-IN-100 exerts antiproliferative effects in ovarian cancer cells and squamous cancer cells. HDAC-IN-100 is applicable for research related to ovarian cancer, squamous cell carcinoma, and Cisplatin (HY-17394)-resistant squamous cell carcinoma .


Cat. No.: EX-A16662	Purity: >98%

	Chemical structure of HDAC-IN-100

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
25mg	get quote

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CAS No.	2390474-88-9
Purity	>98%
Formula	C32H33N5O3
Mol Weight	535.6361

Reference:	[1].Krieger V, et al. Synthesis of Peptoid-Based Class I-Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties. J Med Chem. 2019;62(24):11260-11279.
CoA	CoA of HDAC-IN-100

Smiles:	O=C(NC=1C=CC=CC1N)C2=CC=C(C=C2)CN(C(=O)C3=CC=C(C=C3)N(C)C)CC(=O)NCC=4C=CC=CC4


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