H3B-8800

H3B-8800 is an orally available small molecule modulator of splicing factor 3B subunit 1 (SF3B1). H3B-8800 binds SF3B1 and exhibits significant antitumor activity by eliminating disruption of mRNA splicing.


Cat. No.: EX-A8015	Purity: >98%

	Chemical structure of H3B-8800

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	2400	In-stock
500mg	get quote	In-stock
1g	get quote	In-stock
2g	get quote	In-stock
3g	get quote	Inquire
5g	get quote	Inquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	1825302-42-8
Purity	>98%
Formula	C31H45N3O6
Mol Weight	555.7055
Color	yellow to orange
State	solid powder
Solubility	DMSO : ? 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Seiler M, et al. H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers. Nat Med. 2018 May;24(4):497-504.
CoA	CoA of H3B-8800

Smiles:	C[C@H]1/C=C/[C@@H]([C@](CC[C@H](CC(=O)O[C@@H]1/C(=C/C=C/[C@@H](C)C2=CC=CC=N2)/C)O)(C)O)OC(=O)N3CCN(CC3)C


		Search