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Product Information:

GW843682X

GW843682X is a selective, ATP-competitive inhibitor of PLK1 and PLK3, with IC50s of 2.2 nM and 9.1 nM, respectively.

Cat. No.: EX-A7699    Purity: >98%
Chemical
Chemical structure of GW843682X


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg415In-stock
200mg650In-stock
500mg1000In-stock
1g1550In-stock
2gget quoteIn-stock
5gget quoteIn-stock


SynonymsGW843682
CAS No.660868-91-7
Purity>98%
FormulaC22H18F3N3O4S
Mol Weight477.456
ColorLight yellow to yellow
Statesolid powder
SolubilityDMSO : 33.33 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lansing TJ, et al. In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1. Mol Cancer Ther. 2007 Feb;6(2):450-9. Epub 2007 Jan 31.

[2]. Didier C, et al. Evaluation of Polo-like Kinase 1 inhibition on the G2/M checkpoint in Acute Myelocytic Leukaemia. Eur J Pharmacol. 2008 Sep 4;591(1-3):102-5.

[3]. Ikezoe T, et al. A novel treatment strategy targeting polo-like kinase 1 in hematological malignancies. Leukemia. 2009 Sep;23(9):1564-76.

CoACoA of GW843682X

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