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Product Information:

GTSE1-IN-1

GTSE1-IN-1 is an orally active GTSE1 inhibitor. GTSE1-IN-1 can suppress GTSE1 transcription and expression. GTSE1-IN-1 can inhibit cancer cell proliferation by inducing cell cycle arrest and cell senescence through the persistence of DNA damage. GTSE1-IN-1 can be used for the research of cancer, such as colon and lung cancer.

Cat. No.: EX-A13888    Purity: >98%
Chemical
Chemical structure of GTSE1-IN-1


For research only, Do not use for Human!

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CAS No.3002034-34-3
Purity>98%
FormulaC21H24FN7
Mol Weight393.4606
ColorOff-white to light yellow
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years, 4°C, 2 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sunhui Xing, et al. "Discovery of pyrimidine-2, 4-diamine analogues as efficiency anticancer drug by targeting GTSE1." Bioorganic Chemistry (2024): 107700.

CoACoA of GTSE1-IN-1
Smiles:FC1=CN=C(NC2=CC=C(N3CCN(C)CC3)C=C2)N=C1NC4=CC=C(N)C=C4

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