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Product Information:

GSK963

GSK963 is a chiral, highly potent and selective inhibitor of RIP1 kinase, with an IC50 of 29 nM. GSK963 is a selective and potent inhibitor of necroptosis in murine and human cells in vitro.

Cat. No.: EX-A4784    Purity: 98+%
Chemical
Chemical structure of GSK963


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg485In-stock
250mg685In-stock
500mg950In-stock
1g1350In-stock
5g4285In-stock


SynonymsGSK'963
CAS No.2049868-46-2
Purity98+%
FormulaC14H18N2O
Mol Weight230.3055
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Berger SB, et al. Characterization of GSK'963: a structurally distinct, potent and selective inhibitor of RIP1 kinase. Cell Death Discov. 2015 Jul 27;1:15009.

CoACoA of GSK963
Smiles:CC(C)(C)C(N1N=CC[C@H]1C2=CC=CC=C2)=O

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